Question by Thinker N: Creationists, where do you stand on this..?
Researchers from Cambridge, Glasgow and Greece have discovered a remarkable amount of plasticity in how transcription factors, the proteins that bind to DNA to control the activation of genes, maintain their function over large evolutionary distances.

Reporting in the journal Science, the authors traced the evolution of gene regulation by comparing the binding of evolutionarily conserved transcription factors in the genomes of five vertebrate species — human, dog, mouse, short-tailed opossum and chicken — spanning 300 million years

Paul Flicek, leader of the Vertebrate Genomics Team at EMBL-EBI, an outstation of the European Molecular Biology Laboratory, and coauthor on the paper said “The evolutionary changes in transcription factor binding in the five species have left clues that we can use to explain how function is preserved but not necessarily sequence. What we have learnt is that although the transcription factors regulate similar target genes in all five species, the binding events underpinning this regulation have not been conserved as the species diverged.”

“By studying changes in transcription factor binding, we can understand the evolution of gene regulation,” said Duncan Odom from Cancer Research UK Cambridge Research Institute and coauthor on the paper. He continued: “Differences in gene regulation are central to explaining differences between species, and gene misregulation is a key causative factor in diseases like cancer.”

The results reveal that sequence conservation is not the whole story when it comes to maintaining tissue-specific gene regulation.

What’s your position on these findings..?

Thank you

Best answer:

Answer by So-Crates Resurrected AGAIN
Creationist: “300 Million years? Pshaw – everyone knows the earth is only 6000 years old, so this isnt possible at all…”

Give your answer to this question below!

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